Synergy factors upon combined isoproterenol/TNF-α treatment in C2C12 skeletal muscle.

The strength of the synergies was calculated by dividing the relative mRNA levels upon TNF-α/isoproterenol induction (Z) by the sum of the relative mRNA levels after individual TNF-α (X) and isoproterenol (Y) induction (i.e. Z/(X+Y)). (*) Significant synergy meaning Z/(X+Y) significantly larger than X+Y.

协同效应（synergy）的强度可通过将肿瘤坏死因子α（TNF-α）/异丙肾上腺素（isoproterenol）联合诱导下的相对信使核糖核酸（mRNA）水平（Z），除以单独使用TNF-α（X）与单独使用异丙肾上腺素（Y）诱导后的相对mRNA水平之和（即Z/(X+Y)）计算得到。（*）显著协同效应指Z/(X+Y)显著大于X+Y。