mRNA expression data of 62 human medulloblastoma tumors

To identify molecular subtypes of medulloblastoma we have profiled a series of 62 medulloblastoma tumors. Unsupervised hierarchical cluster analysis of these data identified 5 distinct molecular subtypes. Manuscript submitted. Title: Identification of medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. Authors: Marcel Kool, Jan Koster, Jens Bunt, Nancy E. Hasselt, Arjan Lakeman, Peter van Sluis, Dirk Troost, Netteke Schouten – van Meeteren, Huib N. Caron, Alan Mršić, Bauke Ylstra, Wieslawa Grajkowska, Wolfgang Hartmann, Torsten Pietsch, David Ellison, Steven C. Clifford, Rogier Versteeg. Keywords: tumor classification 62 human medulloblastoma samples were analzyed

为鉴定髓母细胞瘤(medulloblastoma)的分子亚型，我们对62例髓母细胞瘤肿瘤样本进行了表达谱分析。针对上述数据开展无监督层级聚类分析后，成功识别出5种不同的分子亚型。相关研究稿件已提交，论文标题为《具备独特遗传特征谱、通路标记特征及临床病理特征的髓母细胞瘤亚型鉴定》，作者包括Marcel Kool、Jan Koster、Jens Bunt、Nancy E. Hasselt、Arjan Lakeman、Peter van Sluis、Dirk Troost、Netteke Schouten – van Meeteren、Huib N. Caron、Alan Mršić、Bauke Ylstra、Wieslawa Grajkowska、Wolfgang Hartmann、Torsten Pietsch、David Ellison、Steven C. Clifford、Rogier Versteeg。关键词：肿瘤分类。本研究共分析62例人类髓母细胞瘤样本。