caco2_wang
收藏资源简介：
## Dataset Details ### Dataset Description The human colon epithelial cancer cell line, Caco-2, is used as an in vitro model to simulate the human intestinal tissue. The experimental result on the rate of drug passing through the Caco-2 cells can approximate the rate at which the drug permeates through the human intestinal tissue. - **Curated by:** - **License:** CC BY 4.0 ### Dataset Sources - [original data set link](https://tdcommons.ai/single_pred_tasks/adme/#caco-2-cell-effective-permeability-wang-et-al) - [corresponding publication](https://pubs.acs.org/doi/10.1021/acs.jcim.5b00642) ## Citation <!-- If there is a paper or blog post introducing the dataset, the APA and Bibtex information for that should go in this section. --> **BibTeX:** ```bibtex @article{wang2016adme, title={ADME properties evaluation in drug discovery: prediction of Caco-2 cell permeability using a combination of NSGA-II and boosting}, author={Wang, Ning-Ning and Dong, Jie and Deng, Yin-Hua and Zhu, Min-Feng and Wen, Ming and Yao, Zhi-Jiang and Lu, Ai-Ping and Wang, Jian-Bing and Cao, Dong-Sheng}, journal={Journal of Chemical Information and Modeling}, volume={56}, number={4}, pages={763--773}, year={2016}, publisher={ACS Publications} } ```
## 数据集详情 ### 数据集描述 人结肠上皮癌细胞系Caco-2（Caco-2）常被用作体外模型，以模拟人体肠道组织。基于该细胞系的药物透过率实验结果，可近似反映药物穿透人体肠道组织的速率。 - **整理方：** - **授权协议：** CC BY 4.0 ### 数据集来源 - [原始数据集链接](https://tdcommons.ai/single_pred_tasks/adme/#caco-2-cell-effective-permeability-wang-et-al) - [相关研究文献](https://pubs.acs.org/doi/10.1021/acs.jcim.5b00642) ## 引用 **BibTeX格式：** bibtex @article{wang2016adme, title={ADME（吸收、分布、代谢、排泄）特性评估：药物发现中的Caco-2细胞通透性预测——基于NSGA-II与提升算法的组合方案}, author={Wang, Ning-Ning and Dong, Jie and Deng, Yin-Hua and Zhu, Min-Feng and Wen, Ming and Yao, Zhi-Jiang and Lu, Ai-Ping and Wang, Jian-Bing and Cao, Dong-Sheng}, journal={Journal of Chemical Information and Modeling}, volume={56}, number={4}, pages={763--773}, year={2016}, publisher={ACS Publications} }
