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Model description of the AL circuit in Fig 10(left), and its correspondence with the DNP circuit in Fig 10(right).

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https://figshare.com/articles/dataset/Model_description_of_the_AL_circuit_in_Fig_10_left_and_its_correspondence_with_the_DNP_circuit_in_Fig_10_right_/22677198
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Note that for notational simplicity the free parameter values for θ are omitted. Indices under the Model column refer to the following detailed models: (1) OSN to Pre-LN Synapse, (2) Pre-LN BSG, (3) OSN Axon-Terminal, (4) OSN to Post-eLN Synapse, (5) Post-eLN BSG, (6) OSN to Post-iLN Synapse, (7) Post-iLN BSG, (8) OSN to PN Synapse, (9) Post-eLN to PN Synapse, (10) Post-iLN to PN Synapse, (11) PN BSG. The differential equations for each model are detailed under the Equation column, with the corresponding parameters summarized under the Parameters column. Note that under the Parameters column, values for a number of fixed parameters are shown. The circuit has a total of 23 free parameters denoted by the vector θ. For models that correspond to the three differential DNP components shown in Fig 10(right), the correspondences are made explicit on the right side of rows (1–3), (4–5), (6–7) for, respectively, DNP-FF[I], DNP-FF[II] and DNP-FF[III].

为简化符号表示,θ所指代的自由参数值已省略。模型列下的编号对应下述具体模型:(1) 嗅觉感觉神经元(Olfactory Sensory Neuron, OSN)至突触前侧向神经元(Pre-LN)突触;(2) 突触前侧向神经元(Pre-LN)BSG;(3) 嗅觉感觉神经元(OSN)轴突终扣;(4) 嗅觉感觉神经元(OSN)至突触后兴奋性侧向神经元(Post-eLN)突触;(5) 突触后兴奋性侧向神经元(Post-eLN)BSG;(6) 嗅觉感觉神经元(OSN)至突触后抑制性侧向神经元(Post-iLN)突触;(7) 突触后抑制性侧向神经元(Post-iLN)BSG;(8) 嗅觉感觉神经元(OSN)至投射神经元(Projection Neuron, PN)突触;(9) 突触后兴奋性侧向神经元(Post-eLN)至投射神经元(PN)突触;(10) 突触后抑制性侧向神经元(Post-iLN)至投射神经元(PN)突触;(11) 投射神经元(PN)BSG。各模型的微分方程详见方程列,对应参数汇总于参数列。请注意,参数列中展示了若干固定参数的取值。该嗅觉回路共计23个自由参数,以向量θ表示。对于与图10(右侧)所示的三种差分神经通路(Differential Neural Pathway, DNP)组分相对应的模型,其对应关系已在第1-3行、第4-5行、第6-7行右侧明确标注,分别对应DNP-FF[I]、DNP-FF[II]和DNP-FF[III]。
创建时间:
2023-04-21
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