Supplemental Material for Hoffert and Strome, 2019

Table S1. Table of complete MAT locus LOH screen data. <br>Table S2. Top hits identified in MAT locus LOH screen. <br>Table S3. Sector counts of the 217 SCDChet gene deletions analyzed in secondary <i>MET15</i> screen. <br>Table S4. GO Slim Mapper results for the 217 identified genes in the MAT locus screen. <br>Table S5. GO Slim Mapper results for the 100 identified genes in the <i>MET15</i> secondary screen. <br>Table S6. GO Slim Mapper and GO Term Finder results for the 91 genes identified in two or more related independent studies. <br>Table S7. Positional Gene Enrichment analysis of the 217 MAT Top Hits, 100 MAT + MET15 Top hits, and 91 genes identified in 2+ independent studies. <br>Table S8. Human homologs and their associated cancer types for genes identified by the MAT locus screen. <br>Table S9. Human homologs and their associated cancer types for genes identified by multiple independent studies. <br>Table S10. Positional Gene Enrichment analysis of genes identified by similar independent studies. <br>Figure S1. Visual representation of Positional Gene Enrichment data for enriched region on chromosome II.

表S1. MAT基因座（MAT locus）杂合性缺失（LOH）筛选完整数据表。<br>表S2. MAT基因座LOH筛选中鉴定的关键候选基因表。<br>表S3. 217个SCDChet基因（SCDChet gene）缺失株在二次<i>MET15</i>筛选中的扇形计数表。<br>表S4. MAT基因座筛选中217个鉴定基因的GO Slim Mapper分析（GO Slim Mapper）结果表。<br>表S5. 二次<i>MET15</i>筛选中100个鉴定基因的GO Slim Mapper分析结果表。<br>表S6. 两项及以上相关独立研究中鉴定的91个基因的GO Slim Mapper和GO Term Finder分析（GO Term Finder）结果表。<br>表S7. 217个MAT关键候选基因、100个MAT+<i>MET15</i>关键候选基因及两项及以上独立研究中鉴定的91个基因的位置基因富集分析（Positional Gene Enrichment analysis）结果表。<br>表S8. MAT基因座筛选鉴定基因的人类同源基因（Human homologs）及其关联癌症类型表。<br>表S9. 多项独立研究鉴定基因的人类同源基因及其关联癌症类型表。<br>表S10. 相似独立研究鉴定基因的位置基因富集分析结果表。<br>图S1. 染色体II（chromosome II）富集区域的位置基因富集数据可视化图。