Amino acids that interact with emodepside in bold are residues in C-loop that are different due to alternative splicing.

The table shows the amino acids recognized by PYMOL in different filariae that are close and physically interacts with emodepside. Highlighted in red are residues in C-loop that are different due to alternative splicing. Brugia: Bma SLO-1A & Bma SLO-1F; for Onchocerca volvulus: Ovo SLO-1A & Ovo SLO-1D; for equivalent sequences of Dirofilaria immitis: Dim SLO-1; and for Litomosoides sigmodontis: Lsi SLO-1.

本表格展示了PyMOL（PYMOL）在不同丝虫中识别出的、与依莫德司（emodepside）紧密结合并发生物理相互作用的氨基酸残基。其中因可变剪接导致序列差异的C环残基以红色标注。所涉及的物种及对应序列如下：布鲁线虫属（Brugia）的Bma SLO-1A与Bma SLO-1F；旋盘尾丝虫（Onchocerca volvulus）的Ovo SLO-1A与Ovo SLO-1D；犬恶丝虫（Dirofilaria immitis）的等效序列Dim SLO-1；以及棉鼠丝虫（Litomosoides sigmodontis）的Lsi SLO-1。