Mass Spectrometry Metabolomics dataset _ Purine metabolism

Metabolite profiling dataset from cell lines related to Amyotrophic lateral sclerosis (ALS), an age-onset neurodegenerative disorder. The samples were part of a larger project investigating purine metabolism. An untargeted metabolomics analysis was run as part of this project to add evidence to the hypothesis that one of the major genetic causes of ALS leads to purine metabolism dysfunction.

本数据集为与肌萎缩侧索硬化症（Amyotrophic Lateral Sclerosis, ALS）相关的细胞系代谢谱数据集，肌萎缩侧索硬化症是一种随年龄起病的神经退行性疾病。该数据集的样本隶属于一项旨在探究嘌呤代谢的大型研究项目。本项目通过开展非靶向代谢组学分析，旨在为“肌萎缩侧索硬化症的主要遗传病因之一会导致嘌呤代谢功能异常”这一假说提供实证支持。