Horizontal gene transfers and terpene metabolism drive plant-fungal interaction in Marchantia polymorpha.

Marchantia-specific immune mechanisms have not been explored. In this study, we investigated the genetic basis of quantitative resistance in M. polymorpha against the fungal pathogen Colletotrichum nymphaeae, a naturally occurring compatible parasite. Through a transcriptomic approaches, combined with genome-wide association studies (GWAS), we identified key defense-related genes and pathways. The Marchantia polymorpha ssp. ruderalis Tak-1 and CA accessions display striking temporal and functional discrepancies in their differential gene expression in response to C. nymphaeae.

地钱属（Marchantia）特异性免疫机制迄今尚未得到系统研究。本研究以地钱（Marchantia polymorpha）为材料，探究其抵御真菌病原菌睡莲炭疽菌（Colletotrichum nymphaeae）的数量抗性（quantitative resistance）遗传基础，该病原菌为自然存在的亲和性寄生真菌。本研究通过转录组学分析结合全基因组关联分析（Genome-Wide Association Studies, GWAS），鉴定得到关键的防御相关基因及调控通路。地钱（Marchantia polymorpha）糙毛亚种（Marchantia polymorpha ssp. ruderalis）的Tak-1与CA两份种质系，在响应睡莲炭疽菌侵染时的差异基因表达（differential gene expression）模式存在显著的时序与功能差异。