The pituitary hormonal changes related to feed efficiency in pigs

In Poland, conducted for years porcine breeding works focused on improving meat content in the carcass without undertaken to accomplish the more effectiveness of fattening indicators that impact on feed efficiency. At present, feeding and feed conversion became important factors that are especially evident in the countries where the production of fattening pigs is conducted in large farms. In the present study, was attempted to indicate pituitary candidate genes depending on feed conversion ratio (FCR) in native Polish pig breed, Zlotnicka White. The whole pituitary transcriptome was sequenced using next-generation sequencing technology. The obtained results show the differences in gene expression for pathways associated with hormonal regulation and also with Notch and Wnt signaling. Moreover, it was observed that worse FCR in Zlotnicka pigs was associated with a higher fat level in a carcass and a significant higher level of prolactin expression in the pituitary. Overall design: The pituitary hormonal changes related to feed efficiency in pigs experiment was supported by BIOSTRATEG2/297267/14/NCBR/2016

长期以来，波兰的猪育种工作始终以提升胴体肉含量为核心目标，却未着力优化影响饲料利用效率的育肥性能指标。当前，饲喂模式与饲料转化率已成为影响生猪生产的关键因素，这一点在采用大规模猪场开展育肥猪生产的国家中尤为凸显。本研究以波兰本土猪品种兹洛特尼卡白猪（Zlotnicka White）为研究对象，旨在筛选与饲料转化率（Feed Conversion Ratio, FCR）相关的垂体候选基因。研究采用下一代测序技术对垂体全转录组进行了测序。结果显示，与激素调控、Notch及Wnt信号通路相关的基因表达存在显著差异。此外，研究还观察到，兹洛特尼卡白猪的FCR表现越差，其胴体脂肪含量越高，且垂体催乳素的表达水平显著升高。实验整体设计：本项探究猪饲料利用效率相关垂体激素变化的研究，得到了编号为BIOSTRATEG2/297267/14/NCBR/2016的项目资助。