ATN 113 External Dried Blood Spot Testing Results Dataset in Project PrEPare – an Open Label Demonstration Project and Phase II Safety Study of Pre-exposure Prophylaxis Use Among 15 to 17 Year Old Young Men Who Have Sex With Men (YMSM) in the United States

Dried blood spot testing results
Study Description
This pre-exposure prophylaxis (PrEP) demonstration project and phase II safety study aimed to obtain additional data on the safety of emtricitabine/tenofovir (FTC/TDF (Truvada®)). Patterns of use, rates of adherence, and patterns of sexual risk behavior among YMSM (inclusive of transgender women) who were provided with open label FTC/TDF (Truvada®) and information on the safety and efficacy of PrEP from prior studies were evaluated. Furthermore, this project explored the feasibility and acceptability of implementing two different types of efficacious risk reduction interventions prior to the provision of PrEP – Many Men, Many Voices (3MV) and Personalized Cognitive Counseling (PCC).
HIV-1 uninfected 15 to 17 year old young men who have sex with men

干血斑检测结果
研究概况
本研究为一项暴露前预防（Pre-exposure Prophylaxis, PrEP）示范项目及II期安全性研究，旨在获取恩曲他滨/替诺福韦（emtricitabine/tenofovir, FTC/TDF（Truvada®））的额外安全性数据。研究对使用开放式标签恩曲他滨/替诺福韦（FTC/TDF（Truvada®））、并获取了既往研究中暴露前预防（PrEP）安全性与有效性相关信息的男男性行为青年（Young Men who Have Sex with Men, YMSM，含跨性别女性）的用药模式、依从率及性风险行为模式进行了评估。此外，本项目还探索了在提供暴露前预防（PrEP）前实施两种不同类型的有效风险降低干预措施的可行性与接受度——众声男性（Many Men, Many Voices, 3MV）与个性化认知咨询（Personalized Cognitive Counseling, PCC）。
HIV-1未感染的15至17岁男男性行为青年