Results of activity assays (IC50, CC50, EC50, Therapeutic Index (TI)) for selected compounds, with the WNV MTase.

aTherapeutic index was calculates as CC50/EC50;bn.d., not determined.Results of activity assays (IC50, CC50, EC50, Therapeutic Index (TI)) for selected compounds, with the WNV MTase.

治疗指数（Therapeutic Index, TI）以50%细胞毒性浓度（CC50）与50%有效浓度（EC50）的比值计算得到；b.n.d.：未测定（not determined）。针对筛选出的化合物，以西尼罗河病毒甲基转移酶（West Nile Virus Methyltransferase, WNV MTase）为检测靶点所开展的活性检测结果（涵盖半数抑制浓度IC50、CC50、EC50及TI）。