Conserved Gsx2/Ind homeodomain monomer versus homodimer DNA binding defines regulatory outcomes in the fly and mouse

Identification of Gsx2 genomic binding patterns from E12.5 mouse lateral ganglionic eminence (LGEs). Overall design: CUT&RUN analysis was performed to identify Gsx2 genomic binding patterns from dissected E12.5 mouse lateral ganglionic eminence (LGEs) using an endogenously tagged Gsx2-2xFLAG mouse line.

本数据集旨在鉴定小鼠胚胎12.5天（E12.5）外侧神经节隆起（lateral ganglionic eminence, LGE）中Gsx2的基因组结合模式。整体实验设计：采用内源性标记Gsx2-2xFLAG的小鼠品系，对解剖获取的E12.5小鼠外侧神经节隆起样本进行CUT&RUN分析，以明确Gsx2的基因组结合模式。