Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity

Whole genome sequencing of non-activated and activated T cell-derived EV-DNA was performed to determine the coverage of EV-DNA against the host genome and copy number variations between non-activated and activated T cell-derived EV-DNA

本研究对未激活T细胞及激活T细胞来源的细胞外囊泡DNA（Extracellular Vesicle-DNA，EV-DNA）开展全基因组测序，旨在明确该EV-DNA对宿主基因组的覆盖度，以及未激活与激活T细胞来源的EV-DNA之间的拷贝数变异差异。