DNA methylation of hematopoietic stem cells during ontogeny and after enforced proliferative history. Mus musculus

Genome-scale DNA methylation profiles at nucleotide resolution covering the vast majority of CpG islands and a representative sampling of conserved non-coding elements, transposons and other genomic features generated using high-throughput reduced representation bisulfite sequencing (RRBS) for murine hematopoietic stem cells during ontongeny and after enforced prolferative history. Overall design: Analysis of hematopoietic stem cell methylation during ontogeny and after undergoing enforced proliferative history

本数据集涵盖核苷酸分辨率水平的全基因组DNA甲基化谱，覆盖绝大多数CpG岛，并对保守非编码元件、转座子及其他基因组特征完成了代表性采样；相关数据通过高通量简化代表性亚硫酸氢盐测序（high-throughput reduced representation bisulfite sequencing, RRBS）技术生成，受试对象为发育过程中及经历强制增殖历程后的小鼠造血干细胞。实验设计概述：分析造血干细胞在发育过程中及经历强制增殖历程后的甲基化水平。