Pachytene piRNAs target endogenous mRNAs for silencing during meiosis
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Pachytene piRNAs target endogenous mRNAs for silencing during meiosis
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2015-05-22
相关数据集
Ablation of Max expression induces meiotic onset in sexually undifferentiated germ cells. Ablation of Max expression induces meiotic onset in sexually undifferentiated germ cells
MAX (MYC Associated Factor X) is generally known as a mandatory partner for MYC transcription factor, which activates various genes involved in cell growth and metabolism. On the other hand, MAX, when
NIAID Data Ecosystem40
piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development
Eukaryotic genomes harbor invading transposable elements silenced by PIWI-interacting RNAs (piRNAs) to maintain genome integrity in animal germ cells. However, whether piRNAs also regulate endogenous
NIAID Data Ecosystem30
The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation
In eukaryotes, trimethylation of lysine 9 on histone H3 (H3K9) is associated with transcriptional silencing of transposable elements (TEs). In drosophila ovaries, this heterochromatic repressive mark
NIAID Data Ecosystem30
Transcriptome and transposable element dynamics during PIWI regulation in Drosophila ovarian cell cultures. Drosophila melanogaster
This study examines the regulatory capacity of the Piwi protein in the Drosophila OSS cell. Piwi CLIP-Seq, mRNA-Seq and nascent RNAseq datasets were integrated to determine how Piwi proteins where usi
NIAID Data Ecosystem40
piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development [RNA-seq]. piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development [RNA-seq]
Eukaryotic genomes harbor invading transposable elements silenced by PIWI-interacting RNAs (piRNAs) to maintain genome integrity in animal germ cells. However, whether piRNAs also regulate endogenous
NIAID Data Ecosystem30



