five

R283K DNA polymerase beta ternary complex with a templating 8OG and incoming dCTP analog

收藏
Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
下载链接:
https://pdbj.org/mine/summary/4gxj
下载链接
链接失效反馈
官方服务:
资源简介:
R283K DNA polymerase beta ternary complex with a templating 8OG and incoming dCTP analog Descriptor: 2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... Authors: Freudenthal, B.D, Beard, W.A, Wilson, S.H. Deposit date: 2012-09-04 Release date: 2013-01-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion. Nucleic Acids Res., 41, 2013

R283K DNA聚合酶β(DNA polymerase beta)三元复合物,结合模板8-氧代鸟嘌呤(8-oxoguanine, 8OG)与进入的脱氧胞苷三磷酸(dCTP)类似物。 描述物:2'-脱氧-5'-O-[(S)-{二氟[(S)-羟基(膦酰氧基)膦酰基]甲基}(羟基)膦酰基]胞苷、DNA(5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')、DNA(5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3')…… 作者:Freudenthal, B.D, Beard, W.A, Wilson, S.H. 沉积日期:2012-09-04 发布日期:2013-01-16 最后修改日期:2023-09-13 研究方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.2埃(Å) 引用文献:DNA聚合酶小沟相互作用调控模板8-氧代鸟嘌呤损伤的致突变旁路。核酸研究(Nucleic Acids Res.), 41, 2013
创建时间:
2012-09-04
二维码
社区交流群
二维码
科研交流群
商业服务