Peer-Delivered Behavioral Activation Intervention to Improve Adherence to MAT Among Low-Income, Minority Individuals with OUD, Maryland, 2020-2022

This study expands on the Behavioral Intervention to improve adherence to Medication for Opioid Use Disorder (MOUD) among low-income, marginalized individuals in Baltimore, Maryland. Based on Behavioral Activation principles, the "Peer Activate" intervention is specifically designed for implementation by trained peer recovery specialists.
Implementation outcomes included feasibility, acceptability, and fidelity. Feasibility, defined as the suitability and practicality of the approach, was quantitatively measured by the percentage of participants agreeing to participate in the intervention. Acceptability, defined as satisfaction with or tolerability of the approach, was measured quantitatively by session attendance. Fidelity was evaluated through independent ratings of a randomly selected 20% of sessions. The primary effectiveness measure was methadone retention at three months post-intervention, with secondary outcomes including methadone adherence, substance use frequency, and related problems.

本研究针对美国马里兰州巴尔的摩市的低收入边缘化群体，拓展了用于提升阿片类物质使用障碍药物治疗（Medication for Opioid Use Disorder, MOUD）依从性的行为干预方案。该方案基于行为激活（Behavioral Activation）原则，以“同伴激活（Peer Activate）”命名，专为经过培训的同伴康复专员设计实施。
本次研究的实施结局涵盖可行性、可接受性与干预保真度三大维度。其中，可行性指干预方案的适配性与实操性，通过同意参与干预的受试者占比进行量化评估；可接受性指受试者对方案的满意度与耐受程度，以疗程出勤情况进行量化测量；干预保真度则通过随机抽取20%的干预疗程开展独立评分来评估。本研究的主要疗效指标为干预后3个月的美沙酮治疗留存率，次要结局指标包括美沙酮服药依从性、物质使用频率及相关问题。