ATN 080 Monitoring Untoward Event Form [CRF 96] Dataset in Treatment for Depression Among HIV-Infected Youth

Data from Monitoring Untoward Event Form [CRF 96]
Study Description
A two-phase study that tested a behavioral intervention to treat depression in HIV-positive adolescents and young adults. Sites were assigned to either the Combination Cognitive Behavioral Therapy (CBT) and Medication Management (MM) (COMB) group or the Treatment as Usual (TAU) group. Phase I was a 24-week pilot test of CBT and MM manuals at sites assigned to the COMB group. Phase II was a feasibility study of the revised CBT and MM manuals. The intervention targeted symptoms of depression, motivation for medical and depression treatment, adherence to medical care, and wellness behaviors.
HIV-infected adolescents and young adults between the ages of 16-24 years diagnosed with depression

来源于不良事件监测表（病例报告表96，Case Report Form 96，简称CRF 96）的数据
研究概况
本研究为两阶段设计，旨在评估针对人类免疫缺陷病毒（Human Immunodeficiency Virus，HIV）阳性青少年与年轻成人抑郁症的行为干预方案。研究中心被随机分配至联合认知行为疗法（Cognitive Behavioral Therapy，CBT）联合药物管理（Medication Management，MM）组（简称COMB组）或常规治疗组（Treatment as Usual，TAU）。第一阶段为针对分配至COMB组的研究中心开展的为期24周的CBT与MM操作手册预试验。第二阶段为针对修订后的CBT与MM操作手册的可行性研究。该干预方案的干预靶点涵盖抑郁症状、就医与抑郁治疗动机、医疗依从性以及健康行为。
本研究的研究对象为年龄介于16至24岁之间、确诊抑郁症的HIV感染青少年与年轻成人。