Electrochemical Functionalization of Alkenes with 1,3-Dicarbonyl Compounds via Radical Addition

Herein, an electrochemical approach for the functionalization of alkenes with 1,3-dicarbonyl compounds under oxidative conditions is reported. 1,3-Dicarbonyl compounds undergo single-electron transfer (SET) to generate electrophilic radicals, which upon addition to styrene and aliphatic alkenes afford the 1,2-bifunctionalized and α-alkylated products, respectively. The methodology avoids the usage of external oxidants and shows good tolerance with respect to alkene derivatives.

本文报道了一种在氧化条件下利用1,3-二羰基化合物对烯烃进行官能化的电化学方法。1,3-二羰基化合物经单电子转移（single-electron transfer, SET）生成亲电自由基，该自由基分别与苯乙烯和脂肪族烯烃加成后，得到1,2-双官能团化产物与α-烷基化产物。该方法无需使用外部氧化剂，对烯烃衍生物具有良好的耐受性。