Burkholderia cenocepacia J2315 exposed to the aminothiol cysteamine during growth in synthetic cystic fibrosis sputum media (SCFM2). Burkholderia cenocepacia J2315 exposed to the aminothiol cysteamine during growth in synthetic cystic fibrosis sputum media (SCFM2)

Derived from coenzyme A degradation in mammalian cells, the aminothiol cysteamine may represent a promising new adjunct treatment for pulmonary exacerbations in cystic fibrosis (CF). This experiment aims to characterise the effect of sub-MIC cysteamine on Burkholderia cenocepacia J2315. Samples were cultured in SCFM2 (triplicate), and exposed to either cysteamine or a H2O control.

氨基硫醇类化合物半胱胺（cysteamine）源于哺乳动物细胞内的辅酶A降解途径，其或可作为囊性纤维化（CF）患者肺部急性加重的极具潜力的新型辅助治疗手段。本实验旨在表征亚最低抑菌浓度（sub-MIC）半胱胺对洋葱伯克霍尔德菌（Burkholderia cenocepacia）J2315的作用效果。实验样本于SCFM2培养基中进行三次生物学重复培养，并分别施加半胱胺处理或H₂O对照处理。