TSH associated SNPs in extreme phenotype categories.

The table shows results for the quartile-based GRS scores (top panel) and single marker (bottom panel) analyses in extreme phenotype categories, defined as TSH >4 mIU/L (UPPER) or TSH <0.4 mIU/L (LOWER). NORMAL, individuals with TSH within the normal range. OR, odds ratio; StdErr, standard error. A1, effect allele; A2 other allele. SNPs reaching the Bonferroni significance threshold are highlighted in bold.

本表格展示了极端表型类别下基于四分位数的多基因风险评分（Genetic Risk Score, GRS）分析（上半部分）与单标记分析（下半部分）的结果。其中极端表型类别定义为促甲状腺激素（Thyroid-Stimulating Hormone, TSH）>4 mIU/L（UPPER，高分组）或TSH<0.4 mIU/L（LOWER，低分组）。正常组（NORMAL）指TSH处于正常参考范围内的个体。OR（odds ratio，比值比）；StdErr（standard error，标准误）。A1为效应等位基因（effect allele），A2为非效应等位基因（other allele）。达到Bonferroni显著性阈值的单核苷酸多态性（Single Nucleotide Polymorphisms, SNPs）已以粗体标注。