Somatic Mutation Profiles of Glioblastoma Multiforme from TCGA

This dataset contains whole-exome sequencing (WXS)-based somatic mutation data for Glioblastoma Multiforme (GBM) patients, derived from The Cancer Genome Atlas (TCGA). It includes information on genomic alterations such as single nucleotide variants (SNVs) and small insertions/deletions (indels), annotated with mutation consequences, variant classifications, and gene-level information. The dataset is intended for mutation profiling, pathogenicity classification, and integrative genomic analysis in GBM research.

本数据集收录了源自癌症基因组图谱（The Cancer Genome Atlas, TCGA）的多形性胶质母细胞瘤（Glioblastoma Multiforme, GBM）患者的全外显子组测序（whole-exome sequencing, WXS）体细胞突变数据。其涵盖单核苷酸变异（single nucleotide variants, SNVs）与小插入缺失变异（small insertions/deletions, indels）等基因组改变相关信息，并标注了突变效应、变异分类以及基因水平信息。本数据集旨在用于多形性胶质母细胞瘤研究中的突变谱分析、致病性分类及整合基因组分析。