The interplay between dietary selenium, gut microbiota, and diabetes in mouse aging

We revealed that dietary Se deficiency accelerated many age-dependent gut microbial changes in old telomere-humanized C57BL/6J diabetic mice in a sexually dimorphic manner, with Akkermansia muciniphila exhibiting the greatest enrichment in the males.

我们的研究揭示，膳食硒缺乏会以性别二态性的方式，加速老年端粒人源化C57BL/6J糖尿病小鼠体内诸多年龄相关性肠道菌群的变化，其中嗜黏蛋白阿克曼氏菌（Akkermansia muciniphila）在雄性小鼠中的富集程度最高。