Mean values of ACh peak measured in the whole population either with LDF or LSCI at day 1 (D1) and day 7 (D7) in protocols 1 and 2.

The inter-subject variability at a 7-day interval was evaluated by the coefficient of variations (inter-CV) calculated as the SD of CBF values of all subjects divide by the mean CBF of all subjects multiplied by 100. The parameters of the maximal ACh vasodilation measurement obtained after current application are presented in Table 1. Which every way the results were expressed for both techniques, no statistical difference was found between mean values of ACh measured at D1 and mean values of ACh measured at D7. Time to peak corresponds to the time after the end of the current stimulation until the maximal acetylcholine vasodilation is reached.

通过受试者间变异系数（coefficient of variations，inter-CV）评估7天间隔内的受试者间变异性：该系数以所有受试者脑血流量（CBF）值的标准差除以所有受试者的平均脑血流量值后再乘以100计算得到。电流刺激后测得的最大乙酰胆碱（ACh，acetylcholine）血管舒张反应相关参数见表1。无论采用何种方式呈现两种检测技术的结果，第1天（D1）与第7天（D7）测得的乙酰胆碱平均数值之间均未检测到统计学差异。达峰时间指电流刺激结束后直至达到最大乙酰胆碱血管舒张反应所需的时长。