ProjecTILs human reference atlas of CD4+ tumor-infiltrating T cells, version 1

ProjecTILs human reference atlas of CD4+ tumor-infiltrating T cells, generated by semi-supervised STACAS integration of 20 scRNA-seq datasets spanning 7 cancer types. The datasets were obtained from the collection by Zheng et al. Science 2021). The dataset is available as a Seurat object, with subtype labels (functional cluster), sample of origin and several other measurement for each cell stored in the object metadata. The object can be loaded into an R session using the readRDS() function, and directly used as a reference atlas for ProjecTILs (Andreatta et al. Nat Comms 2021).

人类CD4+肿瘤浸润T细胞参考图谱（ProjecTILs）通过半监督STACAS算法整合覆盖7种癌症类型的20个单细胞RNA测序（scRNA-seq）数据集构建而成。该数据集集合源自Zheng等于2021年发表于《Science》的研究。本数据集以Seurat对象格式提供，每个细胞的亚型标签（功能聚类）、来源样本及其他多项测量指标均存储于该对象的元数据（metadata）中。可通过readRDS()函数将该对象加载至R会话环境中，并直接作为ProjecTILs的参考图谱使用，相关方法源自Andreatta等人2021年发表于《Nature Communications》的研究。