Average number of cells which are affected by more than 5 due to a single cell mutation of either a silenced to active cell, or an active to silenced cell, mean (standard deviation) in lattices with dimensions of 90×90 cells.
收藏Figshare2015-12-02 更新2026-04-29 收录
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The upper two rows are for the entire tissue. The middle two rows display silenced cells mutated active, separated into two groups; cells located within two cells of a default line, and those two cells or more from the default line. The lower two rows are likewise for cells that are mutated from active to silenced. Only cells within a distance of 3 cells from the outer boundary of the tissue are included in these counts, to avoid boundary effects. A tissue built by migration has no defects and thus no counts in the 4 lower rows. The average number of cells is taken over all cells and does thus include cells that cause less than change (contributing as zero and thereby lowering the average).
上方两行对应完整组织样本。中间两行展示由沉默态突变为激活态的细胞,并将其分为两组:一组位于默认参考线两侧两个细胞范围内,另一组与该默认参考线间距达两个及以上细胞。下方两行则对应从激活态突变为沉默态的细胞。为避免边界效应,本次统计仅纳入距离组织外边界不超过3个细胞间距的细胞。由迁移过程形成的组织不存在缺陷,因此下方四行无对应统计数据。细胞平均数基于所有细胞计算,因此包含未产生显著变化的细胞(此类细胞贡献值记为0,进而拉低整体平均值)。
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2015-12-02



