RCT with SCLIS use in mVLT for THA patients

RCT which included Perioperative optimisation of fluid status in elective THA patients using Semi-Closed-Loop-Infusion-System (SCLIS) for the detection of transcapillary fluid reflux which served as indication to stop mini fluid challenges. Invasive and noninvasive estimates of plasma dilution responsiveness were used in automated decision making. The results were analysed with an objective to further validate mVLT method (publication in 2014), as well as to validate the Homeostatic Blood States theory and Method (analysis results prepared for publication in 2025).

本随机对照试验（Randomized Controlled Trial, RCT）纳入择期全髋关节置换术（Total Hip Arthroplasty, THA）患者，采用半闭环输液系统（Semi-Closed-Loop-Infusion-System, SCLIS）优化其围手术期液体状态，以检测跨毛细血管液体反流——该反流可作为停止微量液体冲击的指征。血浆稀释反应性的有创与无创评估结果被用于自动化决策过程。研究对结果进行分析，旨在进一步验证mVLT方法（mVLT method，2014年已发表），并验证稳态血液状态理论与方法（Homeostatic Blood States theory and Method，分析结果拟于2025年发表）。