Mouse transcriptome changes by Adrb1 mutation in PS19 mice. Mouse transcriptome changes by Adrb1 mutation in PS19 mice

To investigate effects of the FNSS mutation Adrb1-A187V on the gene expression profile in a mouse model of tauopathy. Overall design: We collected the mouse cortex from both the experimental and control groups at 8 months old of age. 4 mice of each group.

本研究旨在探究FNSS突变Adrb1-A187V对tau蛋白病（tauopathy）小鼠模型基因表达谱的影响。实验设计概述：我们于小鼠8月龄时，分别从实验组与对照组中采集大脑皮层组织，每组各4只小鼠。