Expression quantitative trait locus (eQTLs) summary statistics from normal colon tissue. Based on TOPMed-imputed SNPs and stratified by colon location

We profiled gene expression of non-neoplastic colon from biopsies of 445 healthy individuals, as described in
Díez-Obrero, Virginia et al. “Genetic Effects on Transcriptome Profiles in Colon Epithelium Provide Functional Insights for Genetic Risk Loci.” Cellular and molecular gastroenterology and hepatology vol. 12,1 (2021): 181-197. doi:10.1016/j.jcmgh.2021.02.003.
Here we provide eQTL summary statistics for the entire sample size of BarcUVa-Seq data (n=445) as well as its strata by colon anatomic location, i.e. eQTLs from ascending (n=138), transverse (n= 143) and descending (n=164) colon.

本研究对445名健康个体活检样本中的非肿瘤性结肠组织进行了基因表达谱分析，相关细节已发表于Díez-Obrero, Virginia等人的研究："Genetic Effects on Transcriptome Profiles in Colon Epithelium Provide Functional Insights for Genetic Risk Loci"，刊载于*Cellular and Molecular Gastroenterology and Hepatology*（《细胞与分子胃肠病学和肝病学》）2021年第12卷第1期，页码181-197，DOI:10.1016/j.jcmgh.2021.02.003。
本数据集提供了BarcUVa-Seq测序数据全部样本（n=445）的表达数量性状基因座（expression Quantitative Trait Loci，eQTL）汇总统计结果，同时包含按结肠解剖位置分层的eQTL数据，即来自升结肠（n=138）、横结肠（n=143）与降结肠（n=164）的eQTL数据。