Comparison of methylome data generated with HiSeq X Ten and NovaSeq

To compare the difference of sequencing platform, a sequencing library was served for sequencing on HiSeq X Ten and NovaSeq 6000. Whole-genome bisulfite sequencing library was prepared with tPBAT protocol, then the library was served for sequencing on HiSeq X Ten and NovaSeq 6000.

为比较不同测序平台的差异，本研究采用tPBAT建库方案（tPBAT protocol）制备了全基因组亚硫酸氢盐测序文库（Whole-genome bisulfite sequencing library），随后将该文库分别置于HiSeq X Ten与NovaSeq 6000测序平台上进行测序。