BLISS in mouse embryonic fibroblasts (MEFs)

BLISS a quantitative and versatile genome-wide profiling of DNA breaks in situ in MEFs. 3 conditions tested: Wild Type, Wild Type treated with trans retinoic acid and MEFs having knocked out Ercc1 gene.

BLISS技术是一种可对小鼠胚胎成纤维细胞（Mouse Embryonic Fibroblasts, MEFs）内DNA断裂进行定量、通用型全基因组原位分析的方法。本数据集共测试了三类实验条件：野生型小鼠胚胎成纤维细胞、经反式维甲酸（trans retinoic acid）处理的野生型小鼠胚胎成纤维细胞，以及Ercc1基因敲除的小鼠胚胎成纤维细胞。