Examples of TTTC disease models.

A “1” means the corresponding genotype combination, e.g., “aabb” in (c), would elevate the risk of disease, whereas a “0” means it would not.此处“1”表示对应的基因型组合（例如图(c)中的“aabb”）会增加疾病患病风险，而“0”则表示该基因型组合不会增加该疾病的患病风险。