Flanking sequence database

This dataset contains flanking sequences of T Cell Receptor (TCR) alleles, generated from high-quality genome assemblies provided by the Human Pangenome Reference Consortium (HPRC). Flanking sequences of two lengths (50 bp and 200 bp) were grouped by alleles, and distinct flanking sequences within the same allele are labeled by appending “&flank” to the allele name for ease of identification. File Descriptions: FASTA FilesThese files contain the flanking sequences for TCR alleles, grouped by allele and categorized by length (50 bp or 200 bp): TCRV_cluster_50.fasta: 50 bp flanking sequences for TCRV alleles. TCRV_cluster_200.fasta: 200 bp flanking sequences for TCRV alleles. TCRJ_cluster_50.fasta: 50 bp flanking sequences for TCRJ alleles. TCRJ_cluster_200.fasta: 200 bp flanking sequences for TCRJ alleles. TCRD_cluster_50.fasta: 50 bp flanking sequences for TCRD alleles. TCRD_cluster_200.fasta: 200 bp flanking sequences for TCRD alleles. CSV FilesThese files summarize the haplotypes (h1 for paternal and h2 for maternal) observed in the HPRC dataset and the corresponding flanking sequence groupings for each allele: TCRV_cluster_summary_50.csv: Summary of 50 bp flanking sequence groups for TCRV alleles. TCRV_cluster_summary_200.csv: Summary of 200 bp flanking sequence groups for TCRV alleles. TCRJ_cluster_summary_50.csv: Summary of 50 bp flanking sequence groups for TCRJ alleles. TCRJ_cluster_summary_200.csv: Summary of 200 bp flanking sequence groups for TCRJ alleles. TCRD_cluster_summary_50.csv: Summary of 50 bp flanking sequence groups for TCRD alleles. TCRD_cluster_summary_200.csv: Summary of 200 bp flanking sequence groups for TCRD alleles. The genome assemblies were sourced from the official HPRC GitHub repository:https://github.com/human-pangenomics/HPP_Year1_Assemblies.