Streptococcus pyogenes serotype M89 genome sequencing. Streptococcus pyogenes

GAS serotype M89 invasive infections have significantly increased in the US CDC Active Bacterial Core Surveillance from 2005 to 2014, to gain insight into this epidemic whole genome sequencing was conducted on approximately 1200 GAS M89 isolates of human invasive infections

2005年至2014年间，美国疾控中心（US CDC）主动细菌核心监测项目数据显示，A群链球菌（Group A Streptococcus，GAS）血清型M89侵袭性感染的发病率显著上升。为深入解析此次流行态势，研究人员对约1200株源自人类侵袭性感染的GAS M89分离株开展了全基因组测序。