Mean volumes of lobar white matter lesions (WMLs), regional medial prefrontal cortices, and limbic structures according to the presence of subsyndromal depression and cognitive status.

Analysis of covariance with the Benjamin and Hochberg's correction was used to adjust for sex, age, years of education, and the Mini-Mental State Examination (MMSE) score. Mean (standard deviation). All WML volumes were normalized to total intracranial volume. WML volumes were log-transformed. Age, gender, years of education, and the MMSE score were adjusted before comparison. P-values were adjusted for multiple comparisons. ACC, anterior cingulate cortical volume; OFC, orbitofrontal cortex; NC, normal control; MCI, mild cognitive impairment; AD, Alzheimer's disease; D−, without subsyndromal depression; D+, with subsyndromal depression.

采用本杰明-霍奇金（Benjamin and Hochberg）校正的协方差分析，对性别、年龄、受教育年限以及简易精神状态检查表（Mini-Mental State Examination, MMSE）评分进行校正。数据以均值（标准差）形式呈现。所有脑白质病变（White Matter Lesions, WML）体积均经总颅内体积标准化处理。脑白质病变体积经对数转换。组间比较前已对年龄、性别、受教育年限及MMSE评分进行校正。P值经多重比较校正。ACC，即前扣带回皮层体积；OFC，即眶额叶皮层；NC，即正常对照；MCI，即轻度认知障碍；AD，即阿尔茨海默病；D−，即无亚综合征抑郁；D+，即伴亚综合征抑郁。