Clinical carbapenemase producing K. pneumoniae from Alaska

Four KPC-producing Klebsiella pneumoniae isolates were detected in Alaska patients between 2014-2018. Whole genome sequencing was performed on these isolates to compare genetic information to three blaKPC-2-positive Escherichia coli isolates from gulls to assess evidence for dissemination of the blaKPC gene within Alaska.

2014至2018年间，阿拉斯加的患者体内检出4株产KPC的肺炎克雷伯菌（Klebsiella pneumoniae）分离株。研究人员对上述分离株开展全基因组测序，并将其遗传信息与3株来源于海鸥的blaKPC-2阳性大肠埃希菌（Escherichia coli）分离株进行比对，以评估阿拉斯加境内blaKPC基因传播的相关证据。