Comparisons of effects on risk of FH between LLI and middle-aged subjects.

LLI: long-lived individuals; MI_S: middle-aged controls (southern); MI_N: middle-aged (northern); FH: fasting hyperglycemia;Modelcca, Modeladj and Modelperm corresponded to allele contrast, adjusted for confounding factors (BMI, age, gender, drinking, current smoking and APOE*e4 status) and permutation corrections for multiple comparisons (n = 8000).a between Haplotype2 and all other haplotypes combine.Comparisons of effects on risk of FH between LLI and middle-aged subjects.

LLI：长寿个体（long-lived individuals）；MI_S：南方中年对照人群（middle-aged controls (southern)）；MI_N：北方中年人群（middle-aged (northern)）；FH：空腹高血糖（fasting hyperglycemia）。Modelcca、Modeladj与Modelperm分别对应等位基因对比模型、校正混杂因素（身体质量指数BMI、年龄、性别、饮酒习惯、当前吸烟状态及APOE*e4携带状态）的模型，以及针对多重比较实施置换校正（置换次数n=8000）的模型。[a] 单倍型2与其余所有合并单倍型间的比较。本研究针对长寿个体与中年人群空腹高血糖发病风险的影响效应开展对比分析。