Linear mitochondrial retroplasmid RefSeq Genome. Fusarium oxysporum f. sp. raphani

The pFOXC retroplasmids are small, autonomously replicating DNA molecules in the mitochondria of certain Fusarium oxysporum strains and are among the first linear genetic elements shown to replicate via reverse transcription. There is evidence that reverse transcription is protein primed which suggests that the pFOXC retroplasmids may have an evolutionary relationship with hepadnaviruses, the only other retroelement family known to initiate reverse transcription via a protein primer.

pFOXC逆转录质粒（retroplasmids）是一类小型自主复制DNA分子，存在于部分尖孢镰刀菌（Fusarium oxysporum）菌株的线粒体中，同时也是首批被证实可通过逆转录途径完成复制的线性遗传元件之一。现有研究证据表明，该类质粒的逆转录过程以蛋白质作为引物，这提示pFOXC逆转录质粒可能与嗜肝DNA病毒（hepadnaviruses）存在进化关联——后者是目前已知仅有的另一类可通过蛋白质引物启动逆转录的逆转录元件家族。