PIPKIγ promotes tumor growth by facilitating Warburg effect in colorectal cancer. PIPKIγ promotes tumor growth by facilitating Warburg effect in colorectal cancer

Analysis of gene alterations in SW480 cells upon PIPKIγ knockdown. Our findings reveal a new regulatory role of PIPKIγ in Warburg effect and provide a key contributor in colorectal cancer metabolism with potential therapeutic potentials. Overall design: sh-Ctrl SW480 cells versus sh-PIPKIγ SW480 cells.

PIPKIγ敲低后SW480细胞的基因改变分析。本研究揭示了PIPKIγ在瓦伯格效应（Warburg effect）中的全新调控功能，并为结直肠癌代谢提供了关键调控因子，同时具备潜在的治疗应用价值。整体实验设计：sh-Ctrl SW480细胞与sh-PIPKIγ SW480细胞的对比实验组。