Theasaponin A1 Ameliorates CUMS-Induced Depressive-Like Behaviors in Mice via Modulation of the Gut Microbiota Profile and Restoration of the Endocannabinoid System

This dataset provides supporting evidence for the antidepressant effects of Theasaponin A1. Theasaponin A1 is a saponin compound derived from plants of the Theaceae family, known for its anti-inflammatory and anti-obesity properties, and is safe for oral administration with no toxicity. This study confirms that Theasaponin A1 exhibits antidepressant activity and can be developed as a natural therapeutic agent. The dataset includes data on changes in mouse body weight, behavioral experiments, neuronal counts in the hippocampus, western blot statistical results, and data pointing to the gut microbiota analysis results presented in the study.

本数据集为茶皂苷A1（Theasaponin A1）的抗抑郁作用提供支撑性实验证据。茶皂苷A1是一类源自山茶科（Theaceae）植物的皂苷类化合物，既往研究已证实其具备抗炎与抗肥胖活性，且口服给药安全无毒副作用。本研究证实茶皂苷A1可发挥抗抑郁活性，具备开发为天然治疗药物的潜力。本数据集涵盖小鼠体重变化数据、行为学实验结果、海马区神经元计数数据、蛋白质印迹（western blot）统计结果，以及本研究中呈现的肠道菌群分析相关实验数据。