Radiolabeled Monoclonal Antibody in Treating Patients With Advanced Colorectal Cancer

RATIONALE: Monoclonal antibodies can locate tumor cells and deliver tumor-killing substances, such as radioactive iodine, to them without harming normal cells.
PURPOSE: Phase I trial to study the effectiveness of radiolabeled monoclonal antibody in treating patients with advanced colorectal cancer.

【研究依据】单克隆抗体（monoclonal antibody）可靶向识别肿瘤细胞，并能将杀伤肿瘤的物质（如放射性碘（radioactive iodine））递送至肿瘤病灶处，且不会对正常细胞造成损伤。
【研究目的】开展I期临床试验（Phase I trial），以探究放射性标记单克隆抗体（radiolabeled monoclonal antibody）治疗晚期结直肠癌患者的临床疗效。