Fitness decline in spontaneous mutation accumulation lines of Caenorhabditis elegans with varying effective population sizes

Productivity and survivorship to adulthood for MA lines following 100 consecutive generations of mutation accumulation and the ancestral controls. Column 1 corresponds to the line identifier (MA line or ancestral control line). Column 2 lists the replicate number for each line (where possible, we aimed for five replicates within each line). Columns 3-10 list the worm productivity corresponding to Days 1-8 of the productivity assay. Column 11 is the total productivity summed across Days 1-8. Column 12 lists the number of surviving adults from a pool of L1 larvae initially isolated. Column 13 is the final value for survivorship to adulthood and ranges from 0 to 1 (corresponding to 0 to 100% survivorship to adulthood). Dashes in cells represent lack of data due to hermaphrodite mortality during the assay or inability to enter the replicate line into assay due to sterility or mortality in preceding generations.

本数据集包含经连续100代突变积累的MA株系（Mutation Accumulation）及其祖先对照的成虫发育存活率与繁殖生产力数据。第1列为株系标识符，取值为MA株系或祖先对照株系；第2列为各株系的重复次数，实验设计目标为每个株系设置5次重复（在可行范围内）；第3至10列为繁殖力测定实验中第1至8天的线虫繁殖生产力数据；第11列为第1至8天的总繁殖生产力求和值；第12列为初始分离的L1期幼虫池最终存活的成虫数量；第13列为成虫发育存活率最终值，取值范围为0至1，分别对应0%至100%的成虫存活率。表格单元格中的短横线代表缺失数据，缺失原因包括：检测过程中雌雄同体线虫死亡，或是该重复株系因前代出现不育或死亡而无法纳入本次测定实验。