Placental haeomynamics

The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic pathways leading to normal and abnormal growth, development and health. An important focus of Generation R is to identify early life determinants of common (mostly non-communicable) diseases in adulthood. Pregnant women living in the Rotterdam area, the Netherlands, were included between 2002 and 2006. After birth, the children and their parents have been followed in multiple assessment waves up until young adulthood.

Generation R研究是一项基于人群的前瞻性队列研究（prospective cohort study），随访周期从胎儿期持续至成年阶段。该研究旨在揭示影响正常与异常生长、发育及健康状态的早期环境与遗传通路。Generation R研究的核心关注点之一是明确成年期常见疾病（多为非传染性，non-communicable）的生命早期决定因素。2002年至2006年间，研究纳入了居住于荷兰鹿特丹地区的孕妇群体。儿童出生后，其本人及父母通过多轮评估随访，直至青年期。