Supplementary Data S8 - Read end RPM for PRO-seq data around pausing sites

Supplementary Data S8 of the manuscript "<b>Hypoxia leads to reduced mito-nuclear gene expression and to increased mtDNA transcriptional pausing in human cells</b>" by Shtolz et al.This dataframe contains normalized read end RPM values at identified pause sites across different experimental conditions. It combines data from both mitochondrial DNA strands.<b>Columns:</b><b>cell</b>: Cell line name (e.g., 'hela', 'u87', 'd407')<b>treatment</b>: Experimental condition ('Control' or 'Hypoxia')<b>Position</b>: Mitochondrial DNA position (1-16569) where a pause site was identified<b>Read_End_RPM</b>: Normalized read end counts (Reads Per Million) at the pause site<b>Strand</b>: DNA strand where the pause site occurs ('Positive' for heavy strand or 'Negative' for light strand)

本数据集为Shtolz等人所著论文《缺氧诱导人类细胞线粒体-核基因表达下调并增加线粒体DNA转录暂停》（原英文标题："Hypoxia leads to reduced mito-nuclear gene expression and to increased mtDNA transcriptional pausing in human cells"）的补充数据S8。该数据框包含不同实验条件下已鉴定的转录暂停位点的标准化读取末端RPM值，整合了线粒体DNA（mitochondrial DNA）两条链的相关实验数据。

**字段说明：**
- **cell**：细胞系名称（例如：'hela'、'u87'、'd407'）
- **treatment**：实验分组，可选值为"Control（对照组）"与"Hypoxia（缺氧组）"
- **Position**：线粒体DNA上鉴定出转录暂停位点的物理位置，取值区间为1至16569
- **Read_End_RPM**：该暂停位点处的标准化读取末端计数，即每百万读取数（Reads Per Million，缩写RPM）
- **Strand**：转录暂停位点所在的DNA链，其中"Positive"代表重链，"Negative"代表轻链