Summary of genes regulated by MF101 or LIQ in three cell lines.

Total genes uniquely regulated by the compounds in each cell line, or specifically regulated in different combinations of cell lines. Numbers are the probe set counts. HeLa, Caco-2, or Ishikawa cells were infected with an adenovirus that expresses ERβ for 24 h and were then treated with 125 µg/ml MF101 and 1 µM LIQ for 6 h. Microarrays were performed with WG-6 BeadChips. Genes with fold change more than 1.5 and with BH-adjusted p-value< = 0.05 were considered.

各细胞系中由化合物独有调控的基因，或在不同细胞系组合中特异性调控的基因。数值为探针集（probe set）的计数。将HeLa、Caco-2及Ishikawa细胞以表达雌激素受体β（ERβ）的腺病毒感染24小时，随后用125 μg/ml的MF101与1 μM的LIQ处理6小时。采用WG-6 BeadChips开展微阵列实验。纳入统计的基因需满足表达倍数变化大于1.5，且经BH校正的P值≤0.05。