miRNA profiles in formalin-fixed and paraffin embedded (FFPE) breast cancer tissues. Homo sapiens

We describe a miRNA profiling analysis of matched ductal carcinoma in situ and invasive duct carcinoma components of FFPE breast carcinomas with the purpose to identify potential prognostic markers Overall design: miRNA extracted from 16 matched DCIS/IDC and 24 pure DCIS preparations was profiled using Illumina miRNA BeadChip platform

本研究针对福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）乳腺癌组织中配对的导管原位癌（Ductal Carcinoma In Situ, DCIS）与浸润性导管癌（Invasive Duct Carcinoma, IDC）组分开展微RNA（microRNA, miRNA）表达谱分析，旨在筛选潜在的预后标志物。实验设计概述：从16例配对DCIS/IDC样本及24例纯DCIS样本中提取miRNA，采用Illumina miRNA BeadChip平台完成表达谱检测。