Integrated host-microbe metagenomics of cell-free nucleic acid for sepsis diagnosis in critically ill adults [plasma]

Here we developed a new approach to sepsis diagnosis that integrates host transcriptional profiling with metagenomic broad-range pathogen detection from cell-free plasma RNA and DNA. Comparing gene expression in patients with sepsis versus those without Raw data not provided due to patient privacy concerns.

本研究开发了一种全新的脓毒症（sepsis）诊断方法，该方法整合了宿主转录谱分析与基于无细胞血浆RNA和DNA的宏基因组广谱病原体检测技术。本研究对比了脓毒症患者与非脓毒症患者的基因表达差异；因涉及患者隐私，原始数据暂未公开。