Diabetes insipidus secondary to tuberculous meningoencephalitis with hypothalamic involvement extending to the hypophysis: a case report

Abstract The involvement of Mycobacterium tuberculosis in the central nervous system (CNS) is an uncommon and devastating manifestation of tuberculosis. We report a case of disseminated tuberculosis presenting as meningoencephalitis, hypothalamic involvement with extension to the hypophysis, and secondary insipidus diabetes diagnosed at autopsy.

摘要 结核分枝杆菌（Mycobacterium tuberculosis）累及中枢神经系统（central nervous system, CNS）是结核病的一种少见且极具破坏性的临床表现。本文报告1例经尸检确诊的播散性结核病病例，该患者以脑膜脑炎、下丘脑受累并蔓延至垂体，以及继发性尿崩症为临床表现。