Chromogenic Charge Transfer Cleft-Type Tetrahydrobenzoxanthene Enantioselective Receptors for Dinitrobenzoylamino Acids

A combination of a benzoxanthene cleft-type
receptor with an electron-rich aromatic ring capable of
establishing charge-tranfer interactions provides enantioselective receptors for dinitrobenzoylamino acids. Racemic
mixtures of the receptor can be resolved with TLCs impregnated with the guest. The structure of the complexes has
been established in an X-ray study. Enantiomeric amino
acids provide complexes with different colors.

苯并呫吨裂隙型受体与可形成电荷转移相互作用的富电子芳环相结合，可得到针对二硝基苯甲酰基氨基酸的对映选择性受体。受体的外消旋混合物可通过浸渍有客体分子的薄层色谱（Thin Layer Chromatography, TLC）进行拆分。该受体与客体形成的复合物结构已通过X射线衍射研究得以确定。不同对映体的氨基酸与该受体形成的复合物会呈现出不同的颜色。