Cytotoxic lymphocytes in Kidney Transplant - PNAS - Ishiyama et al 2022

CyTOF dataset of Ishiyama et al., PNAS 2022 "Mass cytometry reveals single-cell kinetics of cytotoxic lymphocyte evolution in CMV-infected renal transplant patients". This dataset includes PBMC CyTOF files by NK-centric panel (singlet cells or live cells after debarcoding) for 11 CMV viremic patients and 9 non-viremic patients. Each patient have 3 to 5 files, which indicate different time points (day 0 of transplantation, at a time point prior to viremia, and then post-viremia at approximately 1-week, 1-month, and long-term (>1 month)). Refer to Figure 1 in the manuscript regarding the time points for each patient.

Ishiyama等人2022年发表于《美国国家科学院院刊》（Proceedings of the National Academy of Sciences, PNAS）的质谱流式细胞术（CyTOF）数据集，对应研究论文题为《质谱流式细胞术揭示巨细胞病毒（CMV）感染肾移植患者中细胞毒性淋巴细胞演化的单细胞动力学》。该数据集包含采用以自然杀伤细胞（NK, Natural Killer）为核心标记的抗体组合获取的外周血单个核细胞（PBMC, Peripheral Blood Mononuclear Cell）CyTOF文件，样本为经去条码处理的单细胞或活细胞，涵盖11例巨细胞病毒血症患者与9例非巨细胞病毒血症患者。每位患者对应3至5份文件，分别对应不同的时间节点：移植术后第0天、病毒血症出现前的时间点，以及病毒血症出现后约1周、1个月和长期（＞1个月）的时间点。各患者的具体时间节点可参考论文中的图1。